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Giants Cardinals Baseball (Associated Press)
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Cardinals and Giants Meet Again With Little Beyond Pride on the Line

There's no ladder to climb here, no October implication lurking behind Tuesday night's tilt at Busch Stadium. This is Game 2 of a three-game series between t...

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Sunday, September 13, 2026
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There's no ladder to climb here, no October implication lurking behind Tuesday night's tilt in St. Louis. This is Game 2 of a three-game series between two teams whose seasons have already told most of their story. But that doesn't mean it's meaningless โ€” for the Cardinals, it's about salvaging a series and playing spoiler down the stretch. For the Giants, it's about answering the only question left in a lost season: can you still beat a team that's given you fits?

That's the strange subplot here. San Francisco has won four of the last five meetings between these two clubs this season, including a sweep of a three-game set in early September that saw the Giants win 7-6, 2-1, and 5-4 โ€” with the Cardinals' lone win in that stretch coming in late September. St. Louis hasn't solved San Francisco much this year, and if recent form is any indication, this rematch won't be easy. The Cardinals arrive on a rough patch of their own, having dropped four of their last five, a stretch that included three straight one-run losses to the Giants and a split series against the White Sox. St. Louis sits at 73-76, outscored by nine runs on the season (4.6 runs scored per game against 4.6 allowed), numbers that scream .500 mediocrity rather than a team playing meaningful September baseball.

San Francisco's numbers are worse across the board. At 62-86, the Giants own the worse record in this matchup by a wide margin, and their run differential of minus-68 is the kind of number that explains why this season has been about evaluation rather than contention. Still, San Francisco enters on a mixed note โ€” losers of two straight to San Diego, but with that head-to-head success against St. Louis fresh in the tank, including three straight wins to close out their prior meeting.

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Giants Cardinals Baseball โ€” Giants Cardinals Baseball

The pitching matchup favors the home club on paper. Andre Pallante takes the mound for St. Louis carrying a 3.452 ERA, a number that's held up as one of the few bright spots in an otherwise disappointing Cardinals campaign. He'll be opposed by Blade Tidwell, whose 4.821 ERA reflects the up-and-down nature of a Giants staff that's been without several key relief arms for extended stretches. If Pallante can command the zone the way he has for most of the year, St. Louis should have the early edge โ€” but this Giants lineup has shown it can scratch out runs even without its full complement of hitters.

Both rosters are dealing with significant absences. The Cardinals will again be without Max Rajcic and Hunter Dobbins on the mound, plus Everson Pereira, JJ Wetherholt, and Blaze Jordan among the position players โ€” a group of injuries that's forced St. Louis to lean on unproven depth for much of the second half. Alec Burleson and Ivรกn Herrera remain sidelined as well, further thinning an offense that's already scuffled of late.

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Cardinals Giants Baseball โ€” Cardinals Giants Baseball

San Francisco's injury list reads even longer. Willy Adames, Matt Chapman, Casey Schmitt, and Harrison Bader are all out, along with a string of relief arms โ€” JT Brubaker, Keaton Winn, Matt Gage, and Joel Peguero among them. It's a lineup that's had to piece things together on both sides of the ball, yet the Giants have somehow found a way to beat this exact opponent in four of their last five tries.

Offensively, the story belongs to Rafael Devers, who's been the best hitter on either roster of late. Devers put up 28 and 38 fantasy points in his last two outings before an off night, and his season average of 14 fantasy points per game leads all players in this preview. Bryce Eldridge has quietly heated up as well, posting 15.5 and 23.5 points in his last two games after an empty performance before that. For St. Louis, Masyn Winn's 22.5-point outing was the highlight of his last three games, while Jordan Walker's production has been streaky โ€” an 18.5-point game sandwiched between two shutouts. Nolan Gorman has offered some consistency at third, with 11 and 13 points in his last two games before going hitless in his most recent trip.

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Cardinals Giants Baseball โ€” Cardinals Giants Baseball

No fantasy projections are available for Tuesday's matchup, so there's no start-or-fade call to make here โ€” just a matchup that favors whichever lineup finds its timing against a shaky starter. Given Pallante's superior form on the mound and the Cardinals' need to salvage this series at home, St. Louis should be able to snap its recent skid against San Francisco. But the Giants have proven all series long โ€” and, all season โ€” that they don't need to be good to be inconvenient.

Prediction: Cardinals 5, Giants 3. St. Louis finally solves San Francisco, evening the season series while setting up a rubber match to close things out.

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